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Obesity (Silver Spring) 32 ,14651473

R.HeimbrgerO.BrnyP.AnderstamB.et al (2015)

That evidence gap makes the delivery method choice more consequential than for most peptides

11,78 Moreover, suppressing either component of system Xc induces ferroptosis by disturbing cystine uptake, then limiting GSH synthesis

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7.5 Critical discussion of translational challenges The translation of ferroptosis-targeting agents for AD faces multiple interconnected challenges, with BBB penetration, off-target effects, long-term safety, and perturbations of iron metabolism and immune function being the most prominent