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Response to treatment with GH therapy is variable of 5 patients reported no response was seen in two patients, an equivocal response seen in another two patients and only one patient responded well to therapy (169)

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2.11 NADPH NADPH plays a crucial role in maintaining cellular redox balance, and each NADPH molecule provides two electrons to ensure the integrity of antioxidant defense mechanisms (105)

NAC supplementation improves positive symptoms and neurocognition in schizophrenia patients with high peripheral oxidative stress [87]

However, the independent effects of vitamin B12 on IR could not be interpreted from the mentioned trials due to combination therapy