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The three nonstructural proteins (NS3/4A, NS5A, and NS5B) are important for HCV replication, and therefore, represent important targets for inhibition by DAA

doi: 10.1542/peds.2005-2824 146 PengX.ChengL.YouY.TangC.RenB.LiY.et al

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Summary: Berberine and L-carnitine can be taken together as no direct interactions are documented, but evidence for their combined use is limited and neither is recommended in UK clinical guidelines