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A customized pressurized chamber was employed in the study which injects a mixture of humidified gas (95% air/5% CO 2 ) through a pressure regulator which maintains the stable pressure within 1 mm Hg from 0 to 200 mm Hg, and it is continuously regulated using a pressure gauge (Ju et al

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doi: 10.3389/fnagi.2018.00004

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