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Energy failure in dopaminergic cells would be expected to siphon energy from other important ATP-dependent homeostatic processes in an attempt to maintain their excitability (including active uptake of neurotransmitters into vesicles) and function

FGD syndromes exhibit an isolated defect in the endogenous production of cortisol without a parallel defect in the production of aldosterone

Goldstein JL, Brown MS

& Galietta, L

[PubMed] [Google Scholar] 235.Imai s, Armstrong cm, Kaeberlein m, Guarente l

A treatment must be validated by rigorous studies demonstrating its superiority over placebo to be considered effective
