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3.1 Age-related macrostructural WM changes A variety of age-related macrostructural WM changes, including reduced WM volume, WM lesions, disrupted WM integrity, and subsequent cortical disconnection have all been observed in normal aging brains (Caligiuri et al., 2015)

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Plant Cell Environ 33:453467 Mittler R (2002) Oxidative stress, antioxidants and stress tolerance

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However, it does not provide details about the specific studies to which it referred, thus leaving uncertain the validity of the chosen MID values, as well as the degree to which the results are clinically meaningful

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