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Lee LJ, Yang Z, Rahman M, Ma J, Kwak KJ, McElroy J, et al
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In humans, P-gp is the product of the MDR1 gene (7) and was among the first identified members of the enormous family of ATP-dependent transporters known as the ABC transporter family (72)

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NPs responsive to GSH encapsulation can deplete intracellular GSH in tumor cells, increasing their sensitivity to oxidative stress
