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HIV-1 Tat-mediated microglial activation by impairing mitophagy/autophagy Mitophagy selectively removes damaged mitochondria through a progression from phagophore to autophagosome and then to lysosome, thereby preserving organelle integrity and cellular homeostasis [82]
At least eleven studies have measured the relationship between elevated B12 and mortality or morbidity in populations known or suspected to have an illness, typically to determine if elevated B12 is an indicator of particular diseases (Arendt, 2013
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The following subsections highlight representative conditions whose mechanistic and therapeutic insights inform the broader field
Methylenetetrahydrofolate reductase and methionine synthase polymorphisms and risk of bladder cancer in a Tunisian population
