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However, this robust inhibition did not affect the concentration of M0 C3 or total C3 acylcarnitine, suggesting that the contribution of valine catabolism to the pool of C3 acylcarnitine is limited by the low expression level of BCAT in plated human hepatocytes and that other substrates make key contributions to these distal pools of intermediates

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10.1146/annurev-biochem-061516-045037 148 TakanoT

Alcoholic liver disease is a significant risk factor for developing cirrhosis and subsequent complications like portal hypertension and variceal bleeding. Medical Expert We stress the need to stop drinking to avoid liver damage and its gut problems