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173,174 PROM2 overexpression is strongly associated with the increased metastatic potential of melanoma, with similar results found in patient-derived xenotransplantation models of RCC and TNBC

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References Ahmed GS, Ali M, Trago IA

However, one study observed that the stimulation of LTD4 increased remodeling markers, such as vimentin and MUC5AC, through the transforming growth factor- (TGF-)/smad2/3-mediated pathway (112)

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