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Rather than targeting appetite or insulin signaling, this peptide is a modified fragment of human growth hormone, specifically amino acids 176 through 191, that directly stimulates fat metabolism without the broader effects of full growth hormone therapy

doi: 10.1152/japplphysiol.00772.2020

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Animal ethics statement All procedures, protocols, and medications were approved by the Johns Hopkins University Animal Care and Use Committee and were performed in accordance with the Association for Research in Vision and Ophthalmology statement for use of animals in ophthalmic and vision research, and the National Institutes of Health guide for the care and use of laboratory animals

10.3390/biomedicines12092051 [DOI] [PMC free article] [PubMed] [Google Scholar] Yoshimura N., Oguchi T., Yokoyama H., Funahashi Y., Yoshikawa S., Sugino Y., et al