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Ying M, Maruschak N, Mansur R, Carvalho A, Cha D, McIntyre R
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Smith, C

When GHK encounters Cu under physiological conditions, the histidine imidazole nitrogen and the N-terminal amine coordinate the metal, with lysine contributing to the binding pocket

M.BellingeriA.WangL.SaremiB.ParysC.et al

Not all medications and nutrients are small enough to get absorbed or need breakdown via gastric enzymes for activation for the sublingual route, but whenever possible there is a benefit to using this route as it bypasses potential damage/absorption issues in the GI tract
