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The glutathione system is a central component of cellular antioxidant defense

Blood 2010;116:15764

Vitamin D signaling maintains intestinal innate immunity and gut microbiota: potential intervention for metabolic syndrome and NAFLD

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However, given the limited sample sizes and observational nature of these studies, such associations should be interpreted cautiously and do not establish causal relationships

Pernicious anaemia is the root cause in up to 80% of these cases and is known to affect women 1.6 times more than men, confirming its autoimmune link
