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doi: 10.1016/j.neuint.2023.105553 38 GongT.LiuL.JiangW.ZhouR

Since its initial characterization, a central theme that has emerged is that ferroptosis represents a fundamental metabolic vulnerabilityone that arises when antioxidant systems fail to detoxify lipid hydroperoxides (LOOH) 1,8,9

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Aberrant activation of key molecular and immune signaling pathways leads to uncontrolled cell proliferation, enhanced tumor cell survival, and maintenance of cancer stem-like cells

Wen, G.-M

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