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Other HAPs under investigation include TH-302 (Evofosfamide), which releases the alkylating agent bromo-isophosphoramide mustard in hypoxic regions

Downregulation of Parkin substrate mitofusin 2, another MAM tethering protein [62], or exogenous expression of Parkin was shown to rescue the disturbance of calcium homeostasis in the mutant fibroblasts [61]

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