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Evaluating the traditional organic formulations for their effects on crop health and disease management in onion is essential for bridging indigenous knowledge with modern scientific validation

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In AD, severe degeneration of cholinergic neurons in the brain substantially reduces acetylcholine (ACh) synthesis and release

130 , 131 Finally, metal ions released by metal oxide NPs promote ROS generation through redox cycling or catalysis via Fenton-like reactions

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

also found the imidazo[1,2- b ]pyridazine scaffold of 89 , and modified substituents in the 3-position of this type skeleton through the introduction of an electron-withdrawing group and hydrophobic substituents to the amide nitrogen to improve permeability and affinity for IKK