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Pharmaceuticals 16:1403

PRPF6 promotes ovarian cancer metastasis and paclitaxel resistance by inducing alternative splicing of SNHG16 (downregulating SNHG16-L while upregulating SNHG16-S), where SNHG16-L inhibits GATA3 transcription through CEBPB binding, ultimately forming a PRPF6/SNHG16-L/CEBPB/GATA3 regulatory axis, with clinical correlations showing PRPF6 overexpression in chemoresistant OC tissues linked to advanced FIGO stages and poor therapeutic outcomes [114]

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Plant Material Processing The extraction of plant material to produce an effective drug usually involves many technical steps

Boezaart, Xavier Sala-Blanch, Enrique Monz, R

According to experiments by Zhu et al., TMAO improved the expression of adenosine diphosphate (ADP) and thrombin to enhance a release of Ca 2+ from intracellular calcium stores, causing platelet aggregation and enhancing thrombosis potential (88)