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Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis

[4] There have also been reports of a feeling of warmth, urticaria, weakness, diaphoresis, nausea, restlessness, tightness of the throat, angioedema, cyanosis, pulmonary edema, and GI bleeding with parenteral administration

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Inflammation of the kidneys filtering units, called glomerulonephritis, is responsible for about 10-20 percent of the extensive kidney damage patients experience, although the affected pathway is common to many forms of progressive kidney damage

doi: 10.3233/JAD-2005-7107