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Later work demonstrated that the combined absence of the p53 target genes encoding the pro-apoptotic BH3-only proteins PUMA and NOXA (and to a lesser extent loss of PUMA alone) rendered lymphoid cells as resistant to DNA damage-inducing agents as loss of p53 itself [8, 9, 22]

10.1073/pnas.87.9.3526 131 HooijmansC

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Here's the simplest approach: 5mg Vial , Quick Reference 10mg Vial , Quick Reference Recommendation Use 2mL of BAC water regardless of vial size

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