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United States (FDA and DSHEA) Not FDA-approved for weight loss or fat-burning claims AOD9604 was previously investigated as a potential obesity treatment, but the FDA has not approved it as a prescription medication (FDA PCAC briefing)

+ A single injection at 50 gives a useful boost lasting four to eight weeks

In non-clinical models, research teams use this compound to examine how nicotinamide metabolism and methylation processes may influence energy expenditure signals, lipid storage markers, and metabolic communication readouts