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Abstract Background: The interplay between bacterial virulence factors and the host innate immune response in pneumococcal meningitis (PM) can result in uncontrolled neuroinflammation, which is known to induce apoptotic death of progenitor cells and post-mitotic neurons in the hippocampal dentate gyrus, resulting in cognitive impairment

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Benzodiazepine Tolerance Prevention The landmark 1999 study by Jelovac and colleagues in the Chinese Journal of Physiology (PMID: 10707891) administered diazepam 5 mg/kg twice daily for 10 days to rats