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These groups are more at risk because their bodies need more B12

In people without pernicious anemia, about 0.5 g/day of B12 is reabsorbed by enterohepatic circulation in which B12-containing bile is secreted by the liver into the digestive tract where the B12 is then reabsorbed via intrinsic factor

1 Vitamin B 12 has been demonstrated to be safe in doses up to 1,000 times the recommended dietary allowance and is safe in pregnancy

Instructing the patient to administer the evening NPH insulin dose at bedtime rather than before dinner helps prevent insulin waning and ensures better glycemic control upon waking

Adams JB, Holloway CE, George F, Quig D: Analyses of toxic metals and essential minerals in the hair of Arizona children with autism and associated conditions, and their mothers

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