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Decreased ATP levels and altered expression of the pro-apoptotic protein BH3-interacting domain death agonist (BID) suggested mitochondrial dysfunction, which, together with ferritinophagy, contributed to lung tissue damage

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10.1021/ci300314k J

Increased NF-B phosphorylation was also observed in the gastrocnemius muscle of rats after 16 weeks of HFD (Sishi et al., 2011)

Targeting endoplasmic reticulum stress for AILI treatment ER stress can be observed in various hepatic injury models, including alcoholic liver disease, nonalcoholic fatty liver disease, ischemia-reperfusion injury and cholestatic liver disease [26]

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