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Fifteen days after the treatment, all the mice were sacrificed and the tumorous tissue obtained (photographs of the tumor: Fig

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This concern was starkly highlighted by a recent multicenter, doubleblind, placebocontrolled randomized trial in early AD: oral DFP 15 mg/kg twice daily for 12 months reduced hippocampal Quantitative Susceptibility Mapping (QSM) yet, paradoxically, accelerated cognitive decline in the intentiontotreat analysis

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Protoporphyrin and deuteroporphyrin normally occur in feces but are primarily products of intestinal bacterial degradation

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Although folic acid is readily absorbed thanks to its single glutamate residue, it is not active as a coenzyme: the enzyme dihydrofolate reductase (DHFR) needs to convert it to tetrahydrofolate for further use [ R , R ]

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