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Notably, when tocotrienol, a water-insoluble analog of vitamin E, was topically administered in microemulsion form at concentrations of 0.010.05%, it exhibited significant efficacy in inhibiting the progression of cataracts in galactose-fed rats

To our knowledge, one intervention study has been conducted in a population of adults with mitochondrial disease
Gibbs S, Jones GT, Earle NJ, Poppe KK, Cameron VA, Fakahau PT, et al

10.1016/j.tem.2017.05.004 21 DejaS.FletcherJ

doi:10.1007/s00018-013-1514-y

doi: 10.1093/eurjhf/hfs067 165 FilippatosGAnkerSDPittBRossingPJosephAKolkhofPet al
