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Compound 2 was added to the solution of ( N - tert -butoxycarbonyl)-L-selenocysteine methyl ester in either methanol or phosphate buffer and incubated for 40 min, 24 h, and 120 h under N 2 gas balloon

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Cisplatin mediates cytotoxicity primarily by binding to DNA and forming intra- and inter-strand crosslinks, resulting in DNA adducts between guanine and adenine bases 84

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Antiinflammatory effects arise through inhibition of NFB and MAPK signaling, reducing levels of COX2, IL6, and TNF in the tumor microenvironment