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10.1016/S0092-8674(00)80611-X Cell 139 YangN.LangenheimJ
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[DOI] [PMC free article] [PubMed] [Google Scholar] 216
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A 2025 systematic review (Vasireddi et al.) and a 2025 narrative review both concluded that while the regenerative signal in animals is compelling, robust human clinical evidence is lacking
Why starting low prevents problems The urge to skip ahead is understandable
