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Dopamine supplementation would be evident, but this hydrophilic neurotransmitter does not cross the BBB and cannot enter the CNS due to brain endothelial tight junctions, active brain endothelial metabolism and lack of transporters [5]

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Each batch is third-party tested to 99% purity by HPLC, with a per-batch Certificate of Analysis (COA) available on request

[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Nirgianakis K., Egger K., Kalaitzopoulos D.R., Lanz S., Bally L., Mueller M.D