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Reintroducing MnSOD restores nitric oxide signaling and improves vascular relaxation, indicating therapeutic promise for this approach in PPHN [90,91]

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10.1016/j.celrep.2013.10.031 22 CracanV.BanerjeeR

In certain cases, mitochondrial activity can reduce sensitivity to ferroptosis

Ligand binding triggers the autocleavage of procaspase-8 into its active form, which initiates downstream caspase activation and the execution of apoptosis

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