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Reduced fatigue
Health Promot Int 19(3):369378

In phagocytes, superoxide anions are produced in substantial quantities by the enzyme NADPH oxidase as part of oxygen-dependent pathogen-killing mechanisms

For adults, the recommended maximum daily dose is 1000 mg

5,10-Methylene tetrahydrofolate (THF) is required for the synthesis of nucleic acids and is reduced to 5-methyl THF by methylene THF reductase, a flavin-dependent enzyme that uses NADPH as a cofactor

It also varies with the activity of PC synthase (PCS, -Glu-Cys transpeptidase), a PC synthesizing enzyme (Fig