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Brevetti G, Perna S, Sabba C, et al

Although mass spectrometry has revealed the diversity of acylcarnitines, research still focuses on a few specific acylcarnitines, suggesting that many acylcarnitines have not been fully explored

This is an autosomal recessive disorder, meaning that two mutations are necessary to have the severe disorder

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Importantly, this study also showed that this results in muscle glycogen sparing during low-intensity exercise (consistent with an increase in fat oxidation) and lower lactate accumulation during high-intensity exercise