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Vascular alterations, such as inflammation, remodeling, stiffness, calcification, and atherosclerosis, may play a role

A recent study found that -ketoglutarate promotes mitophagy and inhibits ROS generation to alleviate osteoarthritis, but these effects can be blocked by Mdivi-1 [64]

This suggests their potential use in regulating immune responses against TB infection [44]

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