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Enzyme instability (tautness) is particularly critical, as it can disrupt entire biological systems by redirecting reactions toward unfavorable mechanistic pathways that stimulate disease progression

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Also, c-Myc expression is higher in glioma cancer stem cells than in non-stem cells [106, 107]

In Alzheimer disease specifically, BDNF deficits are most pronounced in the hippocampus, entorhinal cortex, and prefrontal cortex, the regions earliest and hardest hit by the disease

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the ions, depending in their masses
