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Intravenous administration of vitamin B12 in the treatment of hyperhomocysteinemia associated with end-stage renal disease

The same VEGF pathways are also used by tumours to build their own blood supply [12]

However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

Individuals with increased biotin requirements due to lifestyle, dietary choices, or other health-related factors

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