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Current pharmaceutical design, 17 (16), 16121632

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Jin X., Wang J., Xia Z.M., Shang C.H., Chao Q.L., Liu Y.R., Fan H.Y., Chen D.Q., Qiu F., Zhao F

(2008) Up-regulation and cytoprotective role of epithelial multidrug resistance-associated protein 1 in inflammatory bowel disease

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Thus, pharmacological inhibition of cystine/glutamate antiporter, inhibition of GSH levels, inactivation of GPX4 or iron overload are all critical factors leading to cellular ferroptosis