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Despite a clear association of DSAs with ABMR and poor long term graft outcome, recipients of renal transplants from HLA-identical siblings have been reported to develop accelerated ABMR (5), and immunological graft loss has been observed in DSA-negative patients (6, 7)

applied the CRISPR/Cas9 system to the MDR1 gene in drug-resistant breast cancer MCF-7/ADR cells and found that the sensitivity of DOX was increased using this method (455)

Our results suggest that animals need to curb their antioxidant thiol intake to extend their lifespan, as opposed to supplementing their diet with antioxidants

2.4 SDS-Polyacrylamide Gel Electrophoresis and western Blotting Protein extraction and protein assays were carried out as described previously [10]