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In a rodent model of GBM, treatment with niacin promotes beneficial immune modulation, rejuvenating immunosuppressive myeloid cells and increasing their tumour-fighting abilities (Fig

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CCL3 has been reported to be produced by lipopolysaccharide (LPS)-stimulated microglia and is implicated in the migration and activation of these glial cells in vitro and in vivo (Hayashi et al., 1995