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6 Conclusions and outlook KOA, the most prevalent and representative form of OA, is a globally prevalent and disabling condition

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Prevention of Skin Pigmentation: Glutathione inhibits the activity of tyrosinase and production of melanin which helps to prevent peroxy lipid generation by scavenging reactive oxygen

The negligible increment of ascorbate-glutathione content, ascorbate-glutathione redox and ascorbate-glutathione cycle enzymes activities and dramatic increment in malondialdehyde (MDA), hydrogen peroxide (H 2 O 2 ) and EL were observed in the sensitive genotype VA15

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