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Obesity Obesity is a chronic disease characterized by the accumulation of visceral and subcutaneous fat

Individuals with specific medical conditions, allergies, or taking medications should exercise particular caution when considering alternative medicine practices

2014 Jan 20;20:83-90

Acute glycolytic flux generates lactate that acidifies the microenvironment, proton loads inactivating sirtuin deacetylases to impair peroxisome proliferator-activated receptor gamma coactivator 1 alpha-mediated mitochondrial biogenesis [71] while activating calcium-independent phospholipase A 2 to liberate arachidonic acid [72]

Neurologia 2007;22(5):329-332

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