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As is the case with laser fragmentation of kidney stones, gallstones must have specific specifications to be amenable to laser fragmentation, and the most important of these specifications are small size and small number

This could potentially interfere with the healing cascade in the specific area of injury, so its still a conflicting mechanism.

Analysis of RNAseq data identified changes in gene expression consistent with activation of ERK5 signaling at the 6 h time point
