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The ECM provides structural support to tissues and consists primarily of: collagen elastin glycosaminoglycans GHK-Cu appears to influence this matrix in several ways: stimulating collagen types I and III synthesis promoting elastin production enhancing glycosaminoglycan formation reducing enzymes that degrade collagen Together, these processes help maintain skin elasticity, structural integrity, and resilience

The rats were decapitated under anesthesia with ethyl ether 3 and 24 h after the operation

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Although meprin- and meprin- are differentially expressed during small intestine development in rats 47 , it is not clear how this affects ECM organization during this process

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