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While apoE does not cross the blood-brain barrier (BBB), it is also abundantly expressed in the central nervous system (CNS) by astrocytes, activated microglia, vascular mural cells, choroid plexus cells, and to a lesser extent in stressed neurons [3337]

In these tissues, OCTN2 regulates the uptake of carnitine and acetylcarnitine from the blood

10.1016/j.jbiosc.2014.03.001 27 GeX.ZhengL.ZhuangR.YuP.XuZ.LiuG.et al (2020)

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Cardiac and skeletal muscle abnormalities in cardiomyopathy: comparison of patients with ventricular tachycardia or congestive heart failure