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CRISPR/Cas9-mediated knockout of MFI2 in human melanoma cells resulted in enhanced invasiveness and significant alterations in the expression of genes associated with tumorigenic progression and metastasis [33]

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Squier CA, Kremer MJ

Up to 65% of sporadic SCCs have been found to have loss of heterozygosity at 9q22.3 between D9S162 and D9S165.[77] Oculocutaneous albinism Albinism is a major risk factor for skin cancer in individuals of African ancestry.[20,78] One report describing a cohort of 350 albinos in Tanzania found 104 cutaneous cancers
