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In cutaneous melanoma, melphalan treatment was associated with enhanced expression of the pro-inflammatory cytokines: IL-1, IL-8, and IL-6 and was found to induce apoptosis through ER stress and reactive oxygen species [198]

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[DOI] [PubMed] [Google Scholar] 15.Decroix L, Tonoli C, Soares DD, Tagougui S, Heyman E, Meeusen R