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Simultaneously, the formation of short-lived radical, monodehydroascorbate (MDA ), happen, which may be spontaneously converted to Asc and dehydroascorbate (DHA), and/or might be rapidly reduced to Asc by NAD(P)H-dependent monodehydroascorbate reductase (MDAR, EC 1.6.5.4

Katritch et al., 2013

Sp1-mediated transcriptional activation of the human Pi class glutathione S-transferase promoter

10.1186/s12872-024-04034-3

Atienzar-Aroca S, Flores-Bellver M, Serrano-Heras G et al (2016) Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells

Furthermore, they discovered that in connection with oxidative pentose phosphate, pre-incubating cells with methionine enhanced cellular tolerance to the thiol-oxidizing agent diamide