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Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis

High dose ( 0.5 mg/kg/d) or long-term use may lead to hypoglycemia, especially in patients with diabetes or insulin resistance

EBioMedicine 55 , 102759 (2020)

This model is valuable for targeted drugs screening to treat dormant LSCs in the microenvironment

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