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doi: 10.1016/j.jare.2025.05.036
Vitamin B12 shots are often prescribed for people with: Pernicious anemia (autoimmune destruction of intrinsic factor needed for B12 absorption) Gastrointestinal surgeries (e.g., gastric bypass, ileal resection) Crohns disease or celiac disease Chronic alcoholism Long-term use of acid-reducing medications Vegan diets without supplementation Infants or children with congenital absorption disorders (i.e., vitamin B12 for kids in clinical care) Injections ensure direct delivery into the bloodstream, bypassing the digestive system entirely

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doi: 10.1172/JCI15693
Consequently, we observed that this beneficial effect, after direct injury (permanent ligation) applied to one or two major vessels, could instantly oppose more general damage (maintained intra-abdominal hypertension, either high (grade III) or very high (grade IV)), as all blood vessels which can be compressed with increased intra-abdominal pressure