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A review of hypothalamic-pituitary-adrenal axis function in chronic fatigue syndrome

Activation of TAAR1 triggers phosphorylation cascades via PKC and CaMKII that directly affect NET transporters, resulting in a ceasing of inward reuptake of norepinephrine by NET, and conversion of NET into reverse transport (efflux) mode 14)

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Moreover, glutamine also acts as a precursor for the synthesis of various NEAAs, including asparagine and arginine, implicated in mTORC1 activation 39
