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These formulations exhibit enhanced therapeutic efficacy due to increased residence time and improved drug delivery within the nasal cavity (Altunta and Yener, 2017)

doi: 10.1016/j.biochi.2012.11.004

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A study of LGR-7, a primary receptor of RLX-2, has shown that RLX-2 suppressed collagen-I, PAI-1, and IL-8 expression in ESCs [82] and all these molecules have an important role in fibrosis formation [83, 84]

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