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Psychosocial stress Psychosocial factors such as chronic stress, depression, and social isolation exert bidirectional regulatory effects on physiological aging processes through the brainperipheral organ axis, becoming a critical upstream risk factor for cognitive frailty

Do you remember the model volcano experiment from grade school science class, where you mix baking soda with vinegar and get an eruption of bubbles

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Conflicts of interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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The available evidence indicates that there is a notable impairment in endothelial-derived nitric oxide (NO)-mediated vasodilation in individuals with both insulin-dependent and non-insulin-dependent diabetes mellitus (91)